Detalhe da pesquisa
1.
Comparison of reversed-phase, hydrophilic interaction, and porous graphitic carbon chromatography columns for an untargeted toxicometabolomics study in pooled human liver microsomes, rat urine, and rat plasma.
Metabolomics
; 20(3): 49, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38689195
2.
Sample Matrices for Mass Spectrometry-Based Adherence Monitoring: A Systematic Critical Review.
Ther Drug Monit
; 46(1): 6-15, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37798828
3.
Towards clinical adherence monitoring of oral endocrine breast cancer therapies by LC-HRMS-method development, validation, comparison of four sample matrices, and proof of concept.
Anal Bioanal Chem
; 416(12): 2969-2981, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38488952
4.
Simultaneous analysis of antihyperglycemic small molecule drugs and peptide drugs by means of dual liquid chromatography high-resolution mass spectrometry.
Clin Chem Lab Med
; 61(7): 1300-1308, 2023 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37011023
5.
Closing the gap - development of an analytical methodology using volumetric absorptive microsampling of finger prick blood followed by LC-HRMS/MS for adherence monitoring of antihypertensive drugs.
Anal Bioanal Chem
; 415(1): 167-177, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318313
6.
Outside the limit: questioning the distance restrictions for cooperative miRNA binding sites.
Cell Mol Biol Lett
; 28(1): 8, 2023 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36694129
7.
Optimization of Mass Spectrometry Imaging for Drug Metabolism and Distribution Studies in the Zebrafish Larvae Model: A Case Study with the Opioid Antagonist Naloxone.
Int J Mol Sci
; 24(12)2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37373226
8.
New Psychoactive Substances: Which Biological Matrix Is the Best for Clinical Toxicology Screening?
Ther Drug Monit
; 44(5): 599-605, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35175247
9.
Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterases.
Arch Toxicol
; 96(10): 2755-2766, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35788413
10.
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism.
Molecules
; 27(4)2022 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209079
11.
Recent trends in drugs of abuse metabolism studies for mass spectrometry-based analytical screening procedures.
Anal Bioanal Chem
; 413(22): 5551-5559, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-33792746
12.
Development, validation, and application of a quantitative volumetric absorptive microsampling-based method in finger prick blood by means of LC-HRMS/MS applicable for adherence monitoring of antipsychotics.
Anal Bioanal Chem
; 413(6): 1729-1737, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517479
13.
Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose.
Arch Toxicol
; 95(10): 3223-3234, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34414480
14.
Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systems.
Arch Toxicol
; 95(11): 3539-3557, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453555
15.
Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?
Arch Toxicol
; 95(12): 3681-3693, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34604914
16.
Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis.
Molecules
; 26(5)2021 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33803489
17.
Impact of the used solvent on the reconstitution efficiency of evaporated biosamples for untargeted metabolomics studies.
Metabolomics
; 16(3): 34, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32124055
18.
Current Situation of the Metabolomics Techniques Used for the Metabolism Studies of New Psychoactive Substances.
Ther Drug Monit
; 42(1): 93-97, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31425443
19.
Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoring.
Clin Chem Lab Med
; 58(5): 664-672, 2020 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31665111
20.
Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts.
Arch Toxicol
; 94(6): 2047-2059, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32313995